| 1802 | Georgia Compact, in which the United States promises to extinguish Native American titles to lands inside Georgia. |
| Louisiana Purchase agreement is made. | |
| President Thomas Jefferson proposes voluntary removal of tribes. | |
| Ohio becomes a state. | |
| 1810 | Ogden Land Company acquires preemptive rights to Native lands in New York. |
| 1812 | Louisiana becomes a state. |
| 1813 | Red Stick War begins. |
| 1814 | Treaty of Fort Jackson (1814) concludes the Red Stick War. |
| 1816 | First Seminole War begins. |
| Indiana becomes a state. | |
| 1817 | Alabama becomes a state. |
| Andrew Jackson's forces invade Florida. | |
| Treaty with the Cherokee (1817) provides for land cession and voluntary removal to the West. | |
| 1818 | Treaty with the Delaware (1818) at St. Mary's cedes all Delaware land claims in Indiana. |
| Treaty with the Miami (1818) at St. Mary's provides for their removal from Indiana. | |
| Quapaw cede large area of land in Arkansas. | |
| 1819 | Illinois becomes a state. |
| Mississippi becomes a state. | |
| Treaty of Washington (1819) with the Cherokee provides for land cession and voluntary removal to the West. | |
| Main body of Kickapoo remove west of the Mississippi. | |
| 1820 | Treaty of Doak's Stand (1820), first Choctaw removal treaty, exchanges part of Choctaw land in Mississippi for land west of Arkansas. |
| Delaware remove from Indiana. | |
| 1821 | Missouri becomes a state. |
| Treaty of Indian Springs (1821) cedes Creek lands between the Ocmulgee and Flint Rivers in Georgia. | |
| The Creek pass a law forbidding the sale or cession of Creek land. | |
| 1823 | Treaty of Moultrie Creek (1823) provides for removal of Florida Indians to central Florida. |
| 1824 | Quapaw cede their remaining lands in Arkansas. |
| 1825 | Treaty of Indian Springs (1825) cedes most of remaining Creek lands in Georgia. |
| William McIntosh executed for engineering the Treaty of Indian Springs in violation of Creek law. | |
| 1827 | Alabama enacts legislation to extend laws over Indian lands. |
| Treaty with the Creek (1827) at Fort Mitchell cedes remaining Creek lands in Georgia. | |
| Cherokee write a constitution. | |
| Ho-Chunk (Winnebago) "uprising" against lead miners. | |
| 1828 | Cherokee Phoenix is established with Elias Boudinot as editor. |
| Georgia passes a law attaching Cherokee lands to Georgia counties. | |
| Andrew Jackson is elected president. | |
| Commission is organized to arrange Ottawa and Miami removal. | |
| Western Cherokee remove from Arkansas to Indian Territory. | |
| 1829 | Alabama enacts additional legislation to extend laws over Indian lands. |
| Additional acts by Georgia nullify Cherokee law and deny right of Cherokee to testify against whites. | |
| John H. Eaton becomes secretary of war and urges Congress to establish an organized Indian Territory in the West. | |
| 1830 | Indian Removal Act (1830) passes Congress. |
| Treaty of Dancing Rabbit Creek (1830) with the Choctaw provides for their removal. | |
| Georgia law outlaws Cherokee government and confiscates gold fields. | |
| Georgia passes law requiring license and loyalty oath for whites to remain in Cherokee lands. | |
| Mississippi extends laws over Native Americans within its borders. | |
| Chickasaw Treaty of Franklin is first treaty negotiated under the Indian Removal Act, but becomes null and void. | |
| 1831 | Georgia law requires license and loyalty oath for whites living in Cherokee country. |
| Georgia Guard is authorized by Georgia law. | |
| Lewis Cass becomes secretary of war. | |
| Little Rock Office of Removal and Subsistence is established. | |
| Choctaw removal begins. | |
| Cherokee Nation v. Georgia says Cherokee Nation is not a foreign nation under the Constitution. | |
| Samuel A. Worcester and other missionaries are arrested. | |
| Treaty of Lewistown with Seneca/Shawnee of Lewistown provides for their removal from Ohio. | |
| Treaty with the Shawnee (1831) at Wapakoneta cedes land and provides for their removal from Ohio. | |
| Treaty of with the Ottawa (1831) of Blanchard's Fork and Oquanoxa's Village at Detroit cedes lands and provides for their removal from Ohio. | |
| Treaty with the Menominee (February 8, 1831) adjusts relations with New York Indians. | |
| Treaty of cession and removal is made with the Seneca of Sandusky. | |
| 1832 | Worcester v. Georgia declares Georgia's extension of laws to Cherokee unconstitutional. |
| Treaty of Payne's Landing (1832) provides for Seminole removal. | |
| Georgia enacts legislation to outlaw Cherokee government. | |
| Treaty of Pontotoc (1832) provides for Chickasaw removal. | |
| Black Hawk's War occurs. | |
| Andrew Jackson reelected as president. | |
| Georgia begins confiscating Cherokee property. | |
| Treaty with the Creek (1832) at Washington provides for allotment of Creek lands in Alabama. | |
| Cholera epidemic breaks out in the West. | |
| Stokes Commission is established to prepare Indian Territory tribes for forced removal of others. | |
| Treaty with the Winnebago (1832) at Fort Armstrong cedes lands in southwestern Wisconsin and northern Illinois. | |
| Missouri Kickapoo removed. | |
| Alabama extends its laws over Creek country. | |
| Treaty of McCutcheonsville (1832) with Wyandotte of Ohio cedes lands. | |
| Indian Vaccination Act is passed. | |
| Treaty with Sauk and Fox (1832) at Fort Armstrong cedes their lands east of the Mississippi and provides for their removal. | |
| Treaty with the Appalachicola Band (1832) relinquishes their reservations in Florida and fixes the date for their removal. | |
| Treaty of Camp Tippecanoe with the Potawatomi of the Prairie and Kaukakee cedes Indiana lands. | |
| Treaty of Tippecanoe River with Potawatomi cedes land. | |
| Treaty with Shawne, Etc. (1832) and Delaware cedes lands in Missouri. | |
| Treaty at Tippecanoe River with Potawatomi cedes lands in Indiana and Michigan. | |
| Treaty with Kaskaskia, Etc. (1832) and Peoria at Castor Hill cedes lands in Illinois and Missouri. | |
| Treaty with Menominee cedes lands for Stockbridges, Munsees, Brothertons, and New York Indians. | |
| Treaty with the Piankeshaw and Wea (1832) at Castor Hill cedes lands of in Illinois and Missouri. | |
| 1833 | Treaty with Quapaw (1833) provides for their removal to Indian Territory. |
| Illinois Kickapoo removed. | |
| Sale of Choctaw allotments begins. | |
| Treaty with the Western Cherokee (1833) at Fort Gibson defines limits of Cherokee lands in the West. | |
| Treaty with the Creek (1833) at Fort Gibson defines limits of Creek lands in the West and lays the groundwork for Seminole settlement with the Creek. | |
| Treaty with the Ottawa (1833) of Ohio cedes land and provides for their removal. | |
| Treaty with the Seminole (1833) at Fort Gibson with a Seminole delegation is used by the United States as a removal agreement by the entire tribe. | |
| Treaty with Apalachicola cedes lands and provides for removal. | |
| Treaty of Chicago (1833) with United Chippewa, Ottawa, and Potawatomi, cedes lands and provides for removal. | |
| Supplementary Treaty of Chicago is made with United Chippewa, Ottawa, and Potawatomi residing in the Territory of Michigan south of Grand River. | |
| 1834 | Appalachicola removal begins. |
| Treaty requires Caddo to remove beyond the limits of the United States. | |
| Indian Intercourse Acts designates territories beyond Louisiana, Arkansas, and Missouri "Indian country." | |
| Sale of Creek lands begins. | |
| Chickasaw sign an agreement at Washington that supplements the Treaty of Pontotoc. | |
| Creek voluntary removal begins. | |
| Treaty with the Miami (1834) at the Forks of the Wabash cedes land in Indiana. | |
| Second treaty at the Forks of the Wabash with Miamis cedes land in Indiana. | |
| Treaty with Potawatomi (December 10, 1834) at Tippecanoe River cedes land in Indiana. | |
| Treaty with Potawatomi (December 16, 1834) at Tippecanoe River cedes land in Indiana. | |
| Treaty with Potawatomi (December 17, 1834) at Potawattimie Mills cedes land in Indiana. | |
| Treaty with Potawatomi (December 24, 1834) at Logansport cedes land in Indiana. | |
| 1835 | Treaty with the Caddo (1835) at the Caddo Agency provides for their removal outside the limits of the United States. |
| Treaty of New Echota (1835) provides for Cherokee removal. | |
| 1836 | Arkansas becomes a state. |
| Martin Van Buren is elected president. | |
| Lower Creek engage in a war that results in forced Creek removal. | |
| Seminole removal begins. | |
| Forced Creek removal begins. | |
| Texas becomes a republic. | |
| Menominee sign the Treaty of the Cedars (1836), establishing their Wisconsin reservation. | |
| Treaty of Washington (1836) with Michigan Ottawas and Chippewa cedes land and provides for removal. | |
| Ottawa and Chippewa of Mashigo, Grand River, Michilimackinac, Sault Ste Marie, L'Arbre Croche, and Grand Traverse sign cession and removal treaties. | |
| Treaty with the Chippewa (1836) at Washington cedes land and establishes reservation. | |
| Treaty with the Potawatomi (March 29, 1836) cedes land. | |
| Treaty of Turkey Creek Prairie (1836) with Potawatomi cedes land and provides for removal. | |
| Treaty with the Potawatomi (September 20, 1836) at Chippewanaung cedes land and provides for their removal from Indiana. | |
| Treaty with the Potawatomi (September 22, 1836) at Chippewanaung cedes land and provides for their removal from Indiana. | |
| Treaty with the Potawatomi (September 23, 1836) at Chippewanaung cedes land and provides for their removal from Indiana. | |
| Treaty with the Sauk and Fox (September 27, 1836) at Dubuque County, Wisconsin, cedes land and provides for removal. | |
| Treaty with the Sauk and Fox (September 27, 1836) at Dubuque County, Wisconsin, cedes land. | |
| 1837 | Treaty of Doaksville (1837) provides for Chickasaw removal. |
| Chickasaw removal begins. | |
| General John Wool arrives in Cherokee Nation to prevent rebellion against the Treaty of New Echota. | |
| National banking crisis known as the Panic of 1837 begins. | |
| Treaty of Detroit with Saginaw Chippewa cedes land and provides for removal. | |
| Stockbridge-Munsee Constitution is drafted. | |
| Wreck of the Monmouth kills 311 Creeks. | |
| Michigan becomes a state. | |
| Treaty with Potawatomi (1837) of Indiana at Washington cedes land. | |
| Treaty of St. Peters (1837) with Chippewa cedes land. | |
| Treaty with Sauk and Fox (1837) at Washington cedes land and provides for removal. | |
| Treaty with Winnebago (1837) cedes land and provides for removal. | |
| 1838 | Cherokee forced removal begins. |
| Fort Coffee is abandoned in Indian Territory. | |
| Potawatomi are forced to remove from Indiana on their Trail of Death. | |
| General Winfield Scott arrives in Cherokee Nation to enforce Cherokee removal. | |
| Treaty of Buffalo Creek (1838) with New York tribes cedes land and provides land for them in the West. | |
| Treaty with the Chippewa (1838) of Saginaw cedes land. | |
| Treaty with the Oneida (1838) at Washington with the First Christian and Orchard Parties of Oneida cedes land and establishes reservations. | |
| Treaty with the Miami (1838) cedes land and provides for removal. | |
| 1839 | Major Ridge, John Ridge, and Elias Boudinot, Cherokee, are assassinated. |
| Treaty with the Stockbridge and Munsee (1839) at Stockbridge cedes land and provides for removal of Stockbridge and Munsee in Wisconsin. | |
| Brothertons are made U.S. citizens. | |
| Kickapoo in Kansas remove to Indian Territory. | |
| 1840 | Treaty with the Miami (1840) cedes land and provides for their removal from Indiana. |
| 1842 | Colonel Ethan A. Hitchcock reports on fraud in Indian rationing in the West. |
| U.S. officials declare Second Seminole War ended. | |
| Treaty with the Wyandot (1842) is signed. | |
| Treaty with the Seneca (1842) at Buffalo Creek provides for Seneca removal. | |
| Treaty of LaPointe (1842) with Chippewa of the Mississippi and Lake Superior cedes land. | |
| 1843 | Wyandotte remove from Ohio. |
| 1845 | Florida becomes a state. |
| 1846 | Miami remove from Indiana. |
| Iowa becomes a state. | |
| 1848 | Wisconsin becomes a state. |
| 1851 | Potawatomi remove from Wisconsin. |
| 1854 | Kansas-Nebraska Act organizes Kansas Territory. |
| 1855 | Third Seminole War begins. |
| 1857 | Tonawanda Seneca buy land from Ogden Land Company. |
| 1858 | Billy Bowlegs, the last major Seminole leader, removes from Florida. |
| 1859 | Seminole removal ends. |